/* Original OFL fonts are served locally, including Cyrillic. */
@font-face{font-family:Onest;src:url('/fonts/onest-variable.ttf') format('truetype');font-style:normal;font-weight:100 900;font-display:swap}
@font-face{font-family:'IBM Plex Serif';src:url('/fonts/plex-serif.ttf') format('truetype');font-style:normal;font-weight:400;font-display:swap}
@font-face{font-family:'IBM Plex Serif';src:url('/fonts/plex-serif-italic.ttf') format('truetype');font-style:italic;font-weight:400;font-display:swap}
:root{--reading-font:Onest,system-ui,sans-serif;--heading-font:'IBM Plex Serif',Georgia,serif}
body,.hub-header,.hub-footer,.hub-page{font-family:var(--reading-font);font-weight:350}
body p,body li,body td{font-weight:350}
body button,body select,body input:not([type=file]),body label,body summary{font-family:var(--reading-font)}
body button,body summary,body th,body label{font-weight:450}
body h1,body h2,.hub-intro h1,.hub-section h2,.hub-product-card h2,.panel h2{font-family:var(--heading-font);font-weight:400;letter-spacing:-.035em;text-wrap:balance}
body h3{font-family:var(--reading-font);font-weight:500}
body strong,body b{font-weight:550}
body .hub-brand,body .brand{font-family:-apple-system,BlinkMacSystemFont,'Segoe UI',sans-serif}
/* Keep scientific sequence and code fields monospaced. */
body input[id*=sequence],body textarea,.sequence,code,pre,.mutation,.score{font-family:ui-monospace,SFMono-Regular,monospace}
.hub-products summary{border:1px solid var(--hub-line);border-radius:7px;padding:0 13px;min-height:44px;list-style:none;font-weight:400}
.hub-products summary::-webkit-details-marker{display:none}
.hub-products[open] summary{background:var(--hub-tint);border-color:var(--hub-muted)}
.hub-products div{top:50px}
.hub-header .hub-nav a{min-height:44px;display:inline-flex;align-items:center;padding-block:8px}
.hub-utility{font-weight:400}.hub-theme,.hub-account{min-width:40px;min-height:40px}.hub-languages a{min-height:40px;display:inline-flex;align-items:center}
.eyebrow,.cf-kicker,h2[data-overline]::before{font-family:var(--reading-font);font-weight:450;font-size:10px;line-height:1.5;letter-spacing:.1em;text-transform:uppercase}
h2[data-overline]::before{content:attr(data-overline);display:block;color:var(--muted,var(--hub-muted));margin-bottom:10px;letter-spacing:.1em}
.research-hero,.hub-intro.research-hero{display:grid;grid-template-columns:minmax(0,1.1fr) minmax(0,1fr);gap:clamp(24px,4vw,66px);align-items:center;max-width:none}
.research-copy{min-width:0}.research-copy>.eyebrow{margin-bottom:20px;color:var(--hub-muted)}
.hub-intro.research-hero h1,.public-site .research-hero h1{font-size:clamp(36px,3.65vw,51px);line-height:1.12;letter-spacing:-.04em;margin:0 0 24px}
.hub-intro.research-hero p,.research-hero .hero-copy>p:first-child{font-size:17px;line-height:1.7;max-width:56ch}
.research-hero .hero-copy{max-width:none}.research-hero .hero-copy .subtle{font-size:12px}
.research-art{margin:0;min-width:0;color:var(--hub-accent,var(--accent));align-self:center}
.research-art>svg{display:block;width:100%;height:auto;overflow:visible}
.research-art svg text{font:400 11px var(--reading-font);fill:var(--hub-muted,var(--muted));letter-spacing:.05em}
.art-guide{fill:none;stroke:var(--hub-line,var(--line));stroke-width:1;stroke-dasharray:2 5}
.art-ribbon{fill:none;stroke:currentColor;stroke-width:16;stroke-opacity:.14;stroke-linecap:round}
.art-ribbon-fine{fill:none;stroke:currentColor;stroke-width:1.6;stroke-linecap:round}
.art-axis{fill:none;stroke:currentColor;stroke-opacity:.35;stroke-width:1}
.art-signal{fill:var(--hub-paper,var(--surface));stroke:currentColor;stroke-width:1.6;animation:signal-breathe 5s ease-in-out var(--delay,0s) infinite}
.art-cell{animation:cell-breathe 8s ease-in-out var(--delay,0s) infinite}
.art-cell ellipse{fill:currentColor;fill-opacity:.035;stroke:currentColor;stroke-width:1.2}
.art-cell circle{fill:currentColor;fill-opacity:.18;stroke:currentColor;stroke-width:.7}
.art-trace{fill:none;stroke:currentColor;stroke-width:2;stroke-dasharray:340;stroke-dashoffset:0;animation:trace-reveal 8s ease-in-out infinite}
.art-trace.second{stroke-dasharray:4 5;opacity:.55;animation:none}
.research-art figcaption{display:flex;justify-content:space-between;gap:10px;align-items:center;padding-top:8px;margin:0 5%;font-size:10px;color:var(--hub-muted,var(--muted))}
.art-pause{color:inherit;background:transparent;border:1px solid var(--hub-line,var(--line));border-radius:6px;padding:7px 11px;font:400 11px var(--reading-font);cursor:pointer;min-height:36px;min-width:68px}
.research-art[data-paused=true] *{animation-play-state:paused!important}
@keyframes signal-breathe{0%,100%{stroke-opacity:1;fill-opacity:1}50%{stroke-opacity:.45;fill-opacity:.15}}
@keyframes cell-breathe{0%,100%{transform:scale(1)}50%{transform:scale(1.035)}}
@keyframes trace-reveal{0%,12%{stroke-dashoffset:340}65%,100%{stroke-dashoffset:0}}
@media(hover:hover){.hub-products summary:hover,.art-pause:hover{background:var(--hub-tint,var(--soft))}}
@media(max-width:760px){
 .research-hero,.hub-intro.research-hero{grid-template-columns:1fr;gap:20px}.research-art{width:100%;max-width:450px;margin:0 auto}
 .hub-intro.research-hero h1,.public-site .research-hero h1{font-size:clamp(31px,7.5vw,43px);line-height:1.16}
 .hub-intro.research-hero p,.research-hero .hero-copy>p:first-child{font-size:16px}
 .research-copy>.eyebrow{margin-bottom:15px}.research-art figcaption{font-size:10px}.art-pause{min-height:44px}
 body input:not([type=checkbox]):not([type=radio]),body select,body textarea{font-size:16px}
 .hub-mainnav{gap:12px}.hub-header .hub-nav{gap:4px 16px}.hub-products summary{padding-inline:11px}
 .hub-card-actions a{min-height:44px;display:inline-flex;align-items:center}
 .hub-section p,.hub-section li{line-height:1.75}
 h2[data-overline]::before{font-size:9px;letter-spacing:.08em;margin-bottom:8px}
}
@media(prefers-reduced-motion:reduce){.research-art *{animation:none!important}.art-pause{display:none}}
/* Long Russian scientific words must remain readable on 320px screens. */
body h1,body h2{overflow-wrap:anywhere;hyphens:auto}
/* Direct product entries on the hub: align with the header's right content edge. */
.hub-home-products{display:flex;justify-content:flex-end;align-items:center;gap:10px;margin-left:auto}
.hub-home-products a{box-sizing:border-box;position:relative;isolation:isolate;display:inline-flex;align-items:center;justify-content:center;gap:7px;min-height:44px;padding:10px 14px;border:1px solid var(--hub-line);border-radius:7px;font-size:13px;font-weight:350;white-space:nowrap;transition:transform 160ms ease-out,color 160ms ease-out}
.hub-home-products a::before{content:'';position:absolute;inset:-1px;z-index:-1;border-radius:inherit;background:var(--hub-accent);opacity:0;transition:opacity 160ms ease-out}
.hub-home-products strong{font-weight:550}.hub-home-products svg{display:block;flex-shrink:0;margin-left:4px;align-self:center}
.hub-home-products a:focus-visible,.hub-home-products a:active{color:var(--hub-on-accent,var(--hub-paper))}
.hub-home-products a:focus-visible::before,.hub-home-products a:active::before{opacity:1}
.hub-home-products a:active{transform:scale(.98)}
/* Geometric chevron instead of a font glyph sitting below the text baseline. */
.hub-products summary::after{content:'';width:6px;height:6px;border-right:1px solid currentColor;border-bottom:1px solid currentColor;transform:translateY(-2px) rotate(45deg);margin-left:3px}
@media(hover:hover) and (pointer:fine){.hub-home-products a:hover{color:var(--hub-on-accent,var(--hub-paper));transform:translateY(-1px)}.hub-home-products a:hover::before{opacity:1}.hub-home-products a:active{transform:scale(.98)}}
@media(min-width:1001px){.research-art>svg{width:90%;margin-inline:auto}}
@media(max-width:650px){.hub-home-products{width:100%;justify-content:flex-end;gap:8px}.hub-home-products a{padding-inline:11px;font-size:12px;flex:1}.hub-home-products svg{margin-left:0}}
@media(prefers-reduced-motion:reduce){.hub-home-products a,.hub-home-products a::before{transition:none}.hub-home-products a:hover,.hub-home-products a:active{transform:none}}

/* Quiet illustration controls: no caption or text button below the artwork. */
.research-art{position:relative}
.research-art .art-pause{position:absolute;right:0;bottom:0;box-sizing:border-box;width:36px;height:36px;min-width:36px;min-height:36px;padding:0;display:inline-flex;align-items:center;justify-content:center;border:0;background:transparent;color:var(--hub-muted,var(--muted));opacity:.6}
.research-art .art-pause svg{width:14px;height:14px;display:block}
.art-play-symbol{display:none}.art-pause[aria-pressed=true] .art-play-symbol{display:block}.art-pause[aria-pressed=true] .art-pause-symbol{display:none}
.research-art .art-pause:focus-visible{opacity:1;outline:2px solid currentColor;outline-offset:2px}
@media(hover:hover) and (pointer:fine){.research-art .art-pause{opacity:0}.research-art:hover .art-pause,.research-art .art-pause:focus-visible{opacity:.75}}
@media(max-width:760px){.research-art .art-pause{width:44px;height:44px}}
@media(prefers-reduced-motion:reduce){.research-art .art-pause{display:none}}
/* The wider C gets the same upper-right arrow clearance as the narrow f. */
.product-name[href$="/cellfate/"] .hub-mark{width:35px}
body:has(.cf-public-nav) .brand .mark{position:relative;padding-right:8px}
body:has(.cf-public-nav) .brand .mark span{position:absolute;right:0;top:-1px;margin:0;font:12px/1 Arial,sans-serif;letter-spacing:0}